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2 edition of Collagen metabolism in the estradiol-stimulated uterus. found in the catalog.

Collagen metabolism in the estradiol-stimulated uterus.

Mercedes Susan Mandell

Collagen metabolism in the estradiol-stimulated uterus.

by Mercedes Susan Mandell

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Published .
Written in English


The Physical Object
Pagination152 leaves.
Number of Pages152
ID Numbers
Open LibraryOL14719809M

defects in the metabolism of fibrillar collagen molecules EDS can be caused by a deficiency of collagen-processing enzymes (for example, Jysyl hydroxylase or N-procollagen peptidase) or from mutations in the amino acid sequences of collagen types I, Ill, or V Faulty collagen synthesis causing hyperextensible skin. 4. Boosts Metabolism, Muscle Mass and Energy Output. A boost in collagen may help increase your metabolism by adding lean muscle mass to your frame and helping with the conversion of essential nutrients. One of glycine’s most important roles is helping form muscle tissue by converting glucose into energy that feeds muscle cells.

Increased oxidative stress and its relation with collagen metabolism in knee osteoarthritis Article (PDF Available) in Rheumatology International 27(4) March with Reads. PDF | Uterine leiomyoma is the most common tumour in women with a reported incidence of %. The tumors are benign, composed of smooth muscle cells | .

This important new volume provides a wide-ranging and authoritative account of the uterus and its physiological role in fertility, normal pregnancy and delivery. Acknowledged authorities from around the world discuss a wealth of material including cell and developmental biology, structure, function, anatomy and endocrinology, and clinically important issues such as the cervix during .   Ehlers-Danlos syndrome (EDS) is the name given to a group of more than 10 different inherited disorders; all involve a genetic defect in collagen and connective-tissue synthesis and structure. Ehlers-Danlos syndrome can affect the skin, joints, and blood vessels.


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Collagen metabolism in the estradiol-stimulated uterus by Mercedes Susan Mandell Download PDF EPUB FB2

Metabolism of collagen types I, III, and V in the estradiol-stimulated uterus. Mandell MS, Sodek J. The synthesis and deposition of collagen in uterine tissues stimulated with 17 beta-estradiol was studied in ovariectomized nulliparous rats.

Eight days after ovariectomy g rats were given a single intraperitoneal injection of micrograms Cited by: 8. Metabolism of collagen types I, III, and V in the estradiol-stimulated uterus. M S Mandell and J Sodek; Abstract.

The synthesis and deposition of collagen in uterine tissues stimulated with 17 beta-estradiol was studied in ovariectomized nulliparous rats. Eight days after ovariectomy g rats were given a single intraperitoneal injection of. Nick Shaw, Wolfgang Högler, in Pediatric Bone (Second Edition), Biological Variation.

Several markers of bone and collagen metabolism show circadian variations, usually with higher values at night than during the day [52–55].For example, PICP in children varies by 10–20%, osteocalcin by 30–60%, and Gal-Hyl by 30% over a hour period, although bone ALP does.

Biochemical Pharmacology, Vol. 22, pp. Pergamon Press, Printed in Great Britain. ACCUMULATION OF COLLAGEN IN THE UTERUS OF THE IMMATURE RAT ADMINISTERED ESTRADIOL/3 RICHARD A.

SALVADOR and IRENE TSAI Department of Biochemical Nutrition, Hoffmann-La Roche Inc., Nutley, N.J., U.S.A. {Received 10 May ; accepted21 July ) Abstract—The total protein and collagen Cited by: Administration of μg of oestradiolβ/day to parturient rats strongly inhibits the loss of collagen from the involuting uterus.

Three experiments show that this effect is due to an inhibition of collagen degradation rather than to a stimulation of collagen synthesis. by:   Collagen-associated disorders in relation to POP are still poorly understood.

Until now, connective tissues have been assessed through biochemical evaluation of the collagen metabolism in the local tissues, and only few genetic polymorphisms have been studied [33, 34].

The available data on the changes in local collagen metabolism are often. 1. Introduction. For a long time estrogens have been known as a regulating factor of the metabolism in many connective tissues, like bone, muscle and group of steroid hormones primarily influences the development, maturation and function of the female reproductive tract, but is involved in developmental processes like bone formation and various.

I36 BBA BIOCHIMICA ET BIOPHYSICA ACI A STUDIES ON UTERINE COLLAGENASE IN TISSUE CULTURE I RELATIONSHIP OF ENZYME PRODUCTION TO COLLAGEN METABOLISM JOHN J JEFFREY, ROBERT J COFFEY AND ARTHUR Z EISEN D~wszon of Dermatology, Department of ~']fedzc~e and the Depc~rlment of Bwlog~cal.

Both indicate that collagen synthesis in the uterus takes place in the absence of concomitant fibrillar collagen degradation. Both methods also yield identical results during the involution of the deciduoma, clearly showing the presence of collagen ase activity at this time. Kühn K. The structure of collagen.

Essays Biochem. ; – [Traub W, Piez KA. The chemistry and structure of collagen. Adv Protein Chem. ; – [Gallop PM, Blumenfeld OO, Seifter S. Structure and metabolism of connective tissue proteins. The collagen family members as cell adhesion proteins.

Bioessays ; Morrione TG, Seifter S. Alteration in the collagen content of the human uterus during pregnancy and post partum involution. J Exp Med ; [PMC free article]. Collagen is an essential protein in our body, and in recent years, collagen supplements have taken the health world by storm.

At first, it was only used to have younger and smoother looking skin. But with the evolution of new researches and studies, it is seen that collagen has tons of health and fitness benefits as well. Today I shall discuss selected studies on the effects of estrogens and progesterones on metabolism of collagen not only in bone but in other connective tissues as well.

It is necessary, however, to review briefly some aspects of the chemistry and biology of collagen (1,2) in order to evaluate the results of such studies. The structure of collagen: (a) The basic structural unit of collagen is a triple-stranded helical molecule, and each basic unit is approximately nm in length.

Coordinate Expression of Matrix Metalloproteinase Family Members in the Uterus of Normal, Matrilysin-Deficient, and StromelysinDeficient Mice*. Endocrinology. Collagen occurs in many places throughout the body. Over 90% of the collagen in the body, however, is type I So far, 28 types of collagen have been identified and described.

The five most common types are: • Collagen I: skin, tendon, vascular ligature, organs, bone (main component of the organic part of bone). The bladder, urethra, vagina and uterus are attached to the pelvic walls by a system of connective tissue called the endopelvic fascia.

The structures attaching the uterus to the pelvic wall endopelvic fascia are predominantly fibrous collagen. Boosting collagen may add lean muscle, increase your metabolism, energy and vitality too. ABSTRACT We show that mRNAs for alpha2(I), alpha1(III), and alpha2(V) collagens are regulated by estradiol in the immature rat uterus.

Clones for alpha2(I) and alpha1(III) collagen were induced in a cDNA library prepared from estradiol-stimulated rat uterine mRNA.

Alpha2(I) collagen cDNA was identified by its characteristic hybridization pattern on Northern blots and. Collagen / ˈ k ɒ l ə dʒ ɪ n / is the main structural protein in the extracellular matrix in the various connective tissues in the body. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content.

Collagen consists of amino acids bound together to form a triple helix of elongated fibril. A genetic defect can cause reduced amounts of collagen, collagen disorganisation (collagen is usually organised into bundles), and alterations in the size and shape of collagen.

The subtype of EDS depends on how collagen metabolism has been affected. For example, vascular EDS is caused by decreased or absent synthesis of type III collagen. The total collagen content of the uterus was not significantly altered in estradiol-treated animals, suggesting that estradiol stimulates both the synthesis and degradation of collagen.The uterus contains approximately 80% type I collagen with some type III and a small amount of type IV.

(35) There is a sevenfold increase in the collagen content of the uterus .The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.\/span>\"@ en\/a> ; \u00A0\u00A0\u00A0\n schema:description\/a> \" Control of Hydroxylation of Proline and Lysine Residues -- Structural.